Vasoactive intestinal peptide receptor
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| vasoactive intestinal peptide receptor 1 | |
|---|---|
| Symbol(s): | VIPR1 RDC1, HVR1, VAPC1 |
| Locus: | 3 p22 |
| EC number | [1] |
| EntrezGene | 7433 |
| OMIM | 192321 |
| RefSeq | NM_004624 |
| UniProt | P32241 |
| vasoactive intestinal peptide receptor 2 | |
|---|---|
| Symbol(s): | VIPR2 VPAC2 |
| Locus: | 7 q36.3 |
| EC number | [2] |
| EntrezGene | 7434 |
| OMIM | 601970 |
| RefSeq | NM_003382 |
| UniProt | P41587 |
| adenylate cyclase activating polypeptide 1 (pituitary) receptor type I | |
|---|---|
| Symbol(s): | ADCYAP1R1 PACAPR |
| Locus: | 7 p14 |
| EC number | [3] |
| EntrezGene | 117 |
| OMIM | 102981 |
| RefSeq | NM_001118 |
| UniProt | P41586 |
There are two known receptors for the vasoactive intestinal peptide (VIP) termed VPAC1 and VPAC2.[1][2] These receptors bind both VIP and pituitary adenylate cyclase-activating polypeptide to some degree. Both receptors are members of the 7 transmembrane g protein-coupled family of receptors.
VPAC1 is distributed widely in the CNS, liver, lung, intestine and T-lymphocytes.
VPAC2 is found in the CNS, pancreas, skeletal muscle, heart, kidney, adipose tissue, testis, and stomach.
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Neuropeptide receptors | |
|---|---|
| Hypothalamic hormone receptors |
CRH - FSH - LHRH - TRH - Somatostatin |
| Pituitary hormone receptors |
Vasopressin (1A, 1B, 2) - Oxytocin - LHCG - Type I cytokine receptor (GH, Prolactin) - TSH |
| Other hormone receptors |
Atrial natriuretic factor - Calcitonin - Cholecystokinin - VIP |
| Opioid receptors | |
| Other neuropeptide receptors |
Angiotensin - Bradykinin/Tachykinin (TACR1) - Calcitonin gene-related peptide - Galanin - GPCR neuropeptide (B/W, FF, S, Y) - Neurotensin |
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