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Two-pore channel

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two pore segment channel 1
Symbol(s): TPCN1
Locus: 12 q24.21
EC number [1]
EntrezGene 53373
OMIM 609666
RefSeq NM_017901
UniProt Q9ULQ1
two pore segment channel 2
Symbol(s): TPCN2
Locus: 11 q13.1
EC number [2]
EntrezGene 219931
OMIM [3]
RefSeq NM_139075
UniProt Q8NHX9

Two-pore channels: This small family of 2 members putatively forms cation-selective ion channels. They are predicted to contain two KV-style six-transmembrane domains, suggesting they form a dimer in the membrane. These channels are related to catsper channels channels and, more distantly, TRP channels.

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