Thiothixene

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Thiothixene chemical structure Thiothixene
N,N-dimethyl-9- [3-(4-methylpiperazin-1-yl)propylidene]- thioxanthene-2-sulfonamide IUPAC name
CAS number 5591-45-7	ATC code N05AF04
PubChem 5454	DrugBank none
Chemical formula	{{{chemical_formula}}}
Molecular weight	443.627
Bioavailability	?
Metabolism	Hepatic
Elimination half-life	10-20 hours
Excretion	?
Pregnancy category	?
Legal status	?
Routes of administration	oral, IM

Thiothixene (sold as Navane®) is a thioxanthene drug used as a typical antipsychotic medication. It is a thioxanthene derivative and is the cis isomer of N,Ndimethyl- 9-[3-(4-methyl-1-piperazinyl)-propylidene] thioxanthene-2-sulfonamide.

Although widely used in the treatment of schizophrenia for several decades, thiothixene is seldom used today in favor of atypical antipsychotics such as olanzapine.

See also

• Tranquillizing drugs

References

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