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Biological: Behavioural genetics · Evolutionary psychology · Neuroanatomy · Neurochemistry · Neuroendocrinology · Neuroscience · Psychoneuroimmunology · Physiological Psychology · Psychopharmacology (Index, Outline)
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Thiothixene chemical structure | |
| N,N-dimethyl-9- [3-(4-methylpiperazin-1-yl)propylidene]- thioxanthene-2-sulfonamide IUPAC name | |
| CAS number 5591-45-7 |
ATC code |
| PubChem 5454 |
DrugBank none |
| Chemical formula | {{{chemical_formula}}} |
| Molecular weight | 443.627 |
| Bioavailability | ? |
| Metabolism | Hepatic |
| Elimination half-life | 10-20 hours |
| Excretion | ? |
| Pregnancy category | ? |
| Legal status | ? |
| Routes of administration | oral, IM |
Thiothixene (sold as Navane®) is a thioxanthene drug used as a typical antipsychotic medication. It is a thioxanthene derivative and is the cis isomer of N,Ndimethyl-
9-[3-(4-methyl-1-piperazinyl)-propylidene] thioxanthene-2-sulfonamide.
Although widely used in the treatment of schizophrenia for several decades, thiothixene is seldom used today in favor of atypical antipsychotics such as olanzapine.
Psycholeptics: antipsychotics (N05A)
| |
|---|---|
| Phenothiazine typical antipsychotics | Chlorpromazine • Fluphenazine • Mesoridazine • Perphenazine • Prochlorperazine • Promazine • Thioridazine/Sulforidazine • Trifluoperazine |
| Other typical antipsychotics | Indoles (Molindone) • Butyrophenones (Azaperone, Benperidol, Droperidol, Haloperidol) • Thioxanthenes (Flupentixol, Chlorprothixene, Thiothixene, Zuclopenthixol) • diphenylbutylpiperidines (Fluspirilene, Penfluridol, Pimozide) • other (Loxapine) |
| Atypical antipsychotics | Butyrophenones (Melperone) • Indoles (Sertindole, Ziprasidone) • Benzamides (Sulpiride, Remoxipride, Amisulpride) • diazepines/oxazepines/thiazepines (Clozapine, Olanzapine, Quetiapine) • other (Aripiprazole, Risperidone, Paliperidone, Zotepine) |
- ja:チオチキセン
- sv:Tiotixen
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