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Thiothixene

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Thiothixene chemical structure
Thiothixene

N,N-dimethyl-9-
[3-(4-methylpiperazin-1-yl)propylidene]-
thioxanthene-2-sulfonamide
IUPAC name
CAS number
5591-45-7
ATC code

N05AF04

PubChem
5454
DrugBank
none
Chemical formula {{{chemical_formula}}}
Molecular weight 443.627
Bioavailability  ?
Metabolism Hepatic
Elimination half-life 10-20 hours
Excretion  ?
Pregnancy category  ?
Legal status  ?
Routes of administration oral, IM


Thiothixene (sold as Navane®) is a thioxanthene drug used as a typical antipsychotic medication. It is a thioxanthene derivative and is the cis isomer of N,Ndimethyl- 9-[3-(4-methyl-1-piperazinyl)-propylidene] thioxanthene-2-sulfonamide.

Although widely used in the treatment of schizophrenia for several decades, thiothixene is seldom used today in favor of atypical antipsychotics such as olanzapine.


See alsoEdit

ReferencesEdit

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