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They are divided into two families:
- Type 1, sweet, first characterized in 2001: TAS1R1-TAS1R3
- Type 2, bitter, first characterized in 2000: TAS2R1- TAS2R50, and TAS2R60
- ↑ Nelson G, Hoon MA, Chandrashekar J, Zhang Y, Ryba NJ, Zuker CS (2001). Mammalian sweet taste receptors. Cell 106 (3): 381-90.
- ↑ Adler E, Hoon MA, Mueller KL, Chandrashekar J, Ryba NJ, Zuker CS (2000). A novel family of mammalian taste receptors. Cell 100 (6): 693-702.