Sulforidazine
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| 10-{2-[(RS)-1-Methylpiperidin-2-yl]ethyl}-2-methylsulfonylphenothiazine IUPAC name | |
| CAS number 14759-06-9 | ATC code [[ATC_code_|]][1] |
| PubChem 31765 | DrugBank [2] |
| Chemical formula | {{{chemical_formula}}} |
| Molecular weight | 402.575 g/mol |
| Bioavailability | |
| Metabolism | |
| Elimination half-life | |
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Sulforidazine (brand names: Imagotan, Psychoson, Inofal) a typical antipsychotic and a metabolite of thioridazine; it and mesoridazine are more potent than the parent compound, whose pharmacological effects are believed by some to be largely due to its metabolism into sulforidazine and mesoridazine.[1]
References
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- ↑ Niedzwiecki DM, Mailman RB, Cubeddu LX (Mar 1984). Greater potency of mesoridazine and sulforidazine compared with the parent compound, thioridazine, on striatal dopamine autoreceptors. Journal of Pharmacology & Experimental Therapeutics 228 (3): 636-9.
- PubChem Substance Summary: Sulforidazine National Center for Biotechnology Information.
Psycholeptics: antipsychotics (N05A)
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| Phenothiazine typical antipsychotics | Chlorpromazine • Fluphenazine • Mesoridazine • Perphenazine • Prochlorperazine • Promazine • Thioridazine/Sulforidazine • Trifluoperazine |
| Other typical antipsychotics | Indoles (Molindone) • Butyrophenones (Azaperone, Benperidol, Droperidol, Haloperidol) • Thioxanthenes (Flupentixol, Chlorprothixene, Thiothixene, Zuclopenthixol) • diphenylbutylpiperidines (Fluspirilene, Penfluridol, Pimozide) • other (Loxapine) |
| Atypical antipsychotics | Butyrophenones (Melperone) • Indoles (Sertindole, Ziprasidone) • Benzamides (Sulpiride, Remoxipride, Amisulpride) • diazepines/oxazepines/thiazepines (Clozapine, Olanzapine, Quetiapine) • other (Aripiprazole, Risperidone, Paliperidone, Zotepine) |
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