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Image:Sufentanil Structure.png Sufentanil
N-[4-(methoxymethyl)-1-(2-thiophen-2-ylethyl) -4-piperidyl]-N-phenyl-propanamide IUPAC name
CAS number 56030-54-7	ATC code N01AH03
PubChem 41693	DrugBank APRD00671
Chemical formula	{{{chemical_formula}}}
Molecular weight	386.552 g/mol
Bioavailability
Metabolism
Elimination half-life	265 minutes
Excretion	{{{excretion}}}
Pregnancy category
Legal status	Schedule II (USA)
Routes of administration	Injection

Sufentanil is a synthetic opioid analgesic drug approximately 5 to 10 times more potent than fentanyl. Sufentanil is marketed for use by specialist centres under different trade names, such as Sufenta and Sufentil (India, by Claris Lifesciences Ltd.). Sufentanil was discovered at Janssen Pharmaceutica.

[edit] Uses

The main use of this medication is in operating suites and critical care where pain relief is required for a short period of time. It also offers properties of sedation and this makes it a good analgesic component of anaesthetic regimen during an operation. It is usually administered under the doctor's order through an intravenous route. In some countries sufentanil is only indicated for epidural use, despite this, it is often used off-label both intravenously and intranasally. A transdermal sufentanil patch called Transdur-sufentanil is currently in Stage I clinical trials by ENDO pharmaceuticals for the relief of chronic pain, and has the advantage over fentanyl patches such as Duragesic of only needing to be applied once per week.

[edit] Side effects

It is essential for the administering doctor to be trained in airway management with readily available airway equipment because the drug causes significant respiratory depression and may cause respiratory arrest if given too much too rapidly. Other opioid side effects such as heart rhythm irregularity, blood pressure changes and nausea/vomiting can also be present in patients given this drug and should be dealt with accordingly by the doctor.

[edit] External links

• Link page to external chemical sources.

v·d·e Anesthetic: General anesthetics (N01A)
Barbiturates	Hexobarbital, Methohexital, Narcobarbital, Thiopental
Ethers	Diethyl ether, Desflurane, Enflurane, Isoflurane, Methoxyflurane, Methoxypropane, Sevoflurane, Vinyl ether
Haloalkanes	Chloroform, Halothane, Trichloroethylene
Opioids	Alfentanil, Anileridine, Fentanyl, Phenoperidine, Remifentanil, Sufentanil
Others	Alfaxalone, Droperidol, Etomidate, gamma-Hydroxybutyric acid, Ketamine/Esketamine, Minaxolone, Nitrous oxide, Propanidid, Propofol, Xenon

This page uses content from the English-language version of Wikipedia. The original article was at Sufentanil. The list of authors can be seen in the page history. As with Psychology Wiki, the text of Wikipedia is available under the GNU Free Documentation License.