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The apex of the
posterior horn of the spinal cord is capped by a V-shaped or crescentic mass of translucent, gelatinous neuroglia, termed the substantia gelatinosa of Rolando (or gelatinous substance of posterior horn of spinal cord), which contains both neuroglia cells, and small nerve cells. The gelatinous appearance is due to a very low concentration of myelinated fibers.
It is named for
It corresponds to
Rexed lamina II.
Many μ- and к-
opioid receptors, presynaptic and postsynaptic, are found on these nerve cells; they can be targeted to manage pain of distal origin.
C fibers terminate at this layer.
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This article was originally based on an entry from a
public domain edition of Gray's Anatomy. As such, some of the information contained herein may be outdated. Please edit the article if this is the case, and feel free to remove this notice when it is no longer relevant.
epidural space, dura mater, subdural space, arachnoid mater, subarachnoid space, pia mater, denticulate ligaments, conus medullaris, cauda equina, filum terminale, cervical enlargement, lumbar enlargement, anterior median fissure, dorsal root, dorsal root ganglion, dorsal ramus, ventral root, ventral ramus, sympathetic trunk, gray ramus communicans, white ramus communicans
grey matter: central canal, substantia gelatinosa of Rolando, reticular formation, substantia gelatinosa centralis, interneuron, anterior horn, lateral horn, posterior horn ( column of Clarke, dorsal spinocerebellar tract)
white matter: anterior funiculus: descending ( anterior corticospinal tract, vestibulospinal fasciculus, tectospinal tract), ascending ( anterior spinothalamic tract, anterior proper fasciculus)
lateral funiculus: descending ( lateral corticospinal tract, rubrospinal tract, olivospinal tract), ascending dorsal spinocerebellar tract, ventral spinocerebellar tract, spinothalamic tract, lateral spinothalamic tract, anterior spinothalamic tract, spinotectal tract, posterolateral tract, lateral proper fasciculus, medial longitudinal fasciculus
posterior funiculus: fasciculus gracilis, fasciculus cuneatus, posterior proper fasciculus
It is not known, however, if cocaine acts on this pathway.