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A single-blind experiment is a type of experiment where information that could introduce bias or otherwise skew the result is withheld from the participants. Unlike in a double-blind experiment the experimenter will be in full possession of the facts. A trivial example of a single-blind experiment would be the Pepsi Challenge.
Single-blind experimental design is used where the experimenters either must know the full facts (for example, when comparing sham to real surgery) or where the experimenter will not introduce further bias. In most cases, double-blind experiments are held to achieve a higher standard of scientific rigour.