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The second-generation antidepressants are a class of antidepressants characterized primarily by the era of their introduction (approximately coinciding with the 1970s and 1980s), rather than by their chemical structure or by their pharmacological effect. As a consequence, there is some controversy over which treatments actually belong in this class.
The term "Third generation antidepressant" is sometimes used to refer to even newer antidepressants,[1] often selective serotonin reuptake inhibitors such as; fluoxetine, paroxetine and sertraline, as well as some 'Non SSRI' antidepressants such as mirtazapine, nefazodone, venlafaxine, duloxetine and reboxetine. However, this usage is not universal.
Examples[]
This list is not exhaustive, and different sources vary upon which items should be considered second-generation.
References[]
- ↑ Olver JS, Burrows GD, Norman TR (2001). Third-generation antidepressants: do they offer advantages over the SSRIs?. CNS Drugs 15 (12): 941–54.
External links[]
- MeSH Second-Generation+Antidepressive+Agents
- Diagrams at toxlab.co.uk
- Overview at sagepub.com
- Overview at psyweb.com
- Overview at sciencedaily.com
- Overview at sabryabdelfattah.tripod.com
- [katzung basic and clinical pharmacology - antidepressants
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