Fandom

Psychology Wiki

Retrograde transneuronal degeneration

34,202pages on
this wiki
Add New Page
Talk0 Share

Ad blocker interference detected!


Wikia is a free-to-use site that makes money from advertising. We have a modified experience for viewers using ad blockers

Wikia is not accessible if you’ve made further modifications. Remove the custom ad blocker rule(s) and the page will load as expected.

Assessment | Biopsychology | Comparative | Cognitive | Developmental | Language | Individual differences | Personality | Philosophy | Social |
Methods | Statistics | Clinical | Educational | Industrial | Professional items | World psychology |

Biological: Behavioural genetics · Evolutionary psychology · Neuroanatomy · Neurochemistry · Neuroendocrinology · Neuroscience · Psychoneuroimmunology · Physiological Psychology · Psychopharmacology (Index, Outline)


Retrograde transneuronal degeneration is transneuronal degeneration caused by loss of trophic support from the target. It occurs in presynaptic cells that are sending inputs to injured postsynaptic cells.[1] It is often termed "dying backward." This type of degeneration can be seen in Amyotrophic lateral sclerosis. Loss of Betz cells is a variable effect of this disease but the loss of these cells in this disease demonstrates the “dying-back” (axonopathy) due to the changes in upper motor neurons.[2]

See alsoEdit

ReferencesEdit

  1. Pinching, A.J., and Powell, T.P. (1971). Ultrastructural features of transneuronal degeneration in the olfactory system.. J. Cell. Sci. (8): 253–287..
  2. Eisen, Andrew, and Weber, Markus. (2001). The Motor Cortex and Amyotrophic Lateral Sclerosis. Muscle & Nerve 24 (4): 564–573..

Also on Fandom

Random Wiki