Fandom

Psychology Wiki

Tandem pore domain potassium channel

Redirected from Resting ion channel

34,202pages on
this wiki
Add New Page
Talk0 Share

Ad blocker interference detected!


Wikia is a free-to-use site that makes money from advertising. We have a modified experience for viewers using ad blockers

Wikia is not accessible if you’ve made further modifications. Remove the custom ad blocker rule(s) and the page will load as expected.

Assessment | Biopsychology | Comparative | Cognitive | Developmental | Language | Individual differences | Personality | Philosophy | Social |
Methods | Statistics | Clinical | Educational | Industrial | Professional items | World psychology |

Biological: Behavioural genetics · Evolutionary psychology · Neuroanatomy · Neurochemistry · Neuroendocrinology · Neuroscience · Psychoneuroimmunology · Physiological Psychology · Psychopharmacology (Index, Outline)


Two-pore-domain potassium channels: This family of 15 members form what is known as "leak channels" which possess Goldman-Hodgkin-Katz (open) rectification.[1] These channels are regulated by several mechanisms including oxygen tension, pH, mechanical stretch, and G-proteins. Their name is derived from the fact that the α subunits consist of four transmembrane segments, each containing two pore loops. As such, they structurally correspond to two inward-rectifier α subunits and thus form dimers in the membrane.

Below is a list of the 15 known two-pore-domain human potassium channels:[1]

Gene Name
KCNK1 K2p01.1
KCNK2 K2p02.1
KCNK3 K2p03.1
KCNK4 K2p04.1
KCNK5 K2p05.1
KCNK6 K2p06.1
KCNK7 K2p07.1
KCNK9 K2p09.1
KCNK10 K2p10.1
KCNK12 K2p12.1
KCNK13 K2p13.1
KCNK15 K2p15.1
KCNK16 K2p16.1
KCNK17 K2p17.1
KCNK18 K2p18.1

See alsoEdit

External linksEdit

ReferencesEdit

  1. 1.0 1.1 Goldstein SA, Bayliss DA, Kim D, Lesage F, Plant LD, Rajan S (2005). International Union of Pharmacology. LV. Nomenclature and molecular relationships of two-P potassium channels. Pharmacol Rev 57 (4): 527-40.


This page uses Creative Commons Licensed content from Wikipedia (view authors).

Also on Fandom

Random Wiki