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Remoxipride

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Remoxipride
Remoxipride

3-Bromo-N-[ [(2S)-1-ethylpyrrolidin-2-yl]methyl]-2,6-dimethoxy-benzamide
IUPAC name
CAS number
117591-79-4
ATC code

N05AL04

PubChem
54477
DrugBank
[1]
Chemical formula
Molecular weight 371.27 g/mol
Bioavailability C16H23BrN2O3
Metabolism
Elimination half-life
Excretion
Pregnancy category
Legal status
Routes of administration


Remoxipride is a substituted benzamide which was a promising antipsychotic during clinical trials in the 1990s, but was removed due to possible side effects.

Clinical trials Edit

Remoxipride is a selective D2 antagonist, with a relatively low effective dosage and low incidence of side effects relative to haloperidol. However, after its introduction in Europe, its use was correlated with incidence of aplastic anemia in as many as 1 in 10,000 cases, and it was taken off the market until its relationship to this possible side effect could be studied.

External links Edit

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