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Professor Randolph M. Nesse, M.D. (b. 1948) is an American evolutionary biologist. He is notable for his research on evolutionary psychology and Darwinian medicine, as well as the evolutionary origins of emotions and how natural selection shapes the capacity for mood.

Nesse is a professor of psychology at the University of Michigan, Ann Arbor and a professor of psychiatry at the University of Michigan Medical School. He is also the Director of the Evolution & Human Adaptation Program at University of Michigan.

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  • Nesse, R. M. (1999). Testing evolutionary hypotheses about mental disorders. In S. Stearns (Ed.), Evolution in Health and Disease (pp. 260-266). New York: Oxford University Press.
  • Nesse, R. M., & Williams, G. C. (1995). Why we Get sick. New York: Times Books.
  • Nesse, R. M., & Williams, G. C. (1999). Research designs that address evolutionary questions about medical disorders. In S. Stearns (Ed.), Evolution in Health and Disease (pp. 16-26). New York: Oxford University Press.
  • "Is the market on Prozac?", February 28, 2000 Stanford University Press
  • Nesse, R. M. (1999).Is Depression an Adaptation? Arch Gen Psychiatry. 2000;57:14-20Full text]
  • Kellera,M.C. and Nesse,R.M.(2005). Is low mood an adaptation? Evidence for subtypes with symptoms that match precipitants.Journal of Affective Disorders 86 27–35Full text

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