(New page: {{BioPsy}} '''Radial glial cells''', also called '''Bergman glia''', are a pivotal cell type in the developing CNS involved in key developmental processes, ranging from patterning and neur...) |
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+ | #redirect[[Radial glial cells]] |
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− | '''Radial glial cells''', also called '''Bergman glia''', are a pivotal cell type in the developing CNS involved in key developmental processes, ranging from patterning and neuronal migration to their newly described role as precursors during [[neurogenesis]]. The term 'radial glial cell' refers to their two major characteristics, their long radial processes extending from the ventricular zone (VZ) to the [[Pia mater|pial surface]] and their [[glia]]l properties, such as the content of [[glycogen]] granules or the expression of the [[astrocyte]]-specific [[glutamate]] transporter or the [[glial fibrillary acidic protein]] (GFAP). Notably, recent evidence demonstrates that radial glial cells characterized by long radial processes and astroglial properties constitute the majority of precursors during [[neurogenesis]]. Indeed, all radial glial cells divide throughout neurogenesis and give rise to the majority of projection neurons in the [[cerebral cortex]]. |
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− | ==Sources== |
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− | * Hartfuss E, Forster E, Bock HH, Hack MA, Leprince P, Luque JM, Herz J, Frotscher M, Gotz M. (2003) Reelin signaling directly affects radial glia morphology and biochemical maturation. Development 130(19):4597-609. PMID 12925587 |
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− | ==External links== |
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− | * {{Dorlands|g_07|12393469}} |
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− | {{Nervous tissue}} |
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− | [[Category:Neuroscience]] |
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− | [[Category:Glial cells]] |
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− | {{enWP|Radial glia}} |
Latest revision as of 23:26, 2 October 2013
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