Wikia

Psychology Wiki

Posterior column-medial lemniscus pathway

Talk0
34,142pages on
this wiki
Revision as of 11:49, October 8, 2006 by Lifeartist (Talk | contribs)

Assessment | Biopsychology | Comparative | Cognitive | Developmental | Language | Individual differences | Personality | Philosophy | Social |
Methods | Statistics | Clinical | Educational | Industrial | Professional items | World psychology |

Biological: Behavioural genetics · Evolutionary psychology · Neuroanatomy · Neurochemistry · Neuroendocrinology · Neuroscience · Psychoneuroimmunology · Physiological Psychology · Psychopharmacology (Index, Outline)


Posterior column-medial lemniscus pathway
Gray759
Originating in peripheral sensory receptors, the posterior column-medial lemniscus pathway transmits fine touch and conscious proprioceptive information to the brain.
Latin {{{Latin}}}
[[List of subjects in Gray's Anatomy:{{{GraySubject}}}#Gray.27s_page_.23|Gray's]] subject #{{{GraySubject}}}
System Somatosensory system
MeSH {{{MeshNumber}}}
[[Image:{{{Image2}}}|190px|center|]]
{{{Caption2}}}

The posterior column-medial lemniscus pathway is the sensory pathway responsible for transmitting fine touch and conscious proprioceptive information from the body to the cerebral cortex.

The name comes from the two structures that the sensation travels up: the posterior (or dorsal) columns of the spinal cord, and the medial lemniscus in the brainstem. Because the posterior columns are also called dorsal columns, the pathway is often called the dorsal column-medial lemniscus system, or DCML for short. (Also called posterior column-medial lemniscus or PCML pathway).

Journey of the posterior column-medial lemniscus pathway

Discriminative sensation is well developed in the fingers of humans, and allows us to feel fine textures and determine what an unknown object in our hands is without looking at it.

This fine sensation is detected by Meissner's corpuscles that lie in the dermis of the skin close to the epidermis. When these structures are stimulated by slight pressure, an action potential is started.

The action potential travels up an axon (the cell body of the neuron will be in a dorsal root ganglion). (The neurons are classified as unipolar, so they are regarded as having just one long process, an axon.) So the sensation travels from the skin, along the axon, past the neuronal cell body, and into the dorsal column of the spinal cord.

The axons continue inside the spinal cord, running up the posterior (dorsal) column. Axons from the lower body are most medial (closer to the midline), and run in the gracile tract of the spinal column. Sensory axons from the upper body enter the spinal cord later, so are more lateral and travel up the cuneate tract.

At the brainstem

At the level of the closed medulla oblongata, these axons synapse with neurons in the gracile and cuneate nuclei. The secondary neurons (that start in the nuclei) cross over to the other side of the medulla (as internal arcuate fibres) to form the medial lemniscus.

At the medulla, the medial lemniscus is orientated perpendicular to the way the fibres travelled in the posterior columns. For example, in the columns, lower limb is medial, upper limb is more lateral. At the medial leminiscus, axons from the leg are more ventral, arm fibres more dorsal. Fibres from the trigeminal nerve (supplying the head) come in dorsal to the arm fibres, and travel up the lemniscus too.

The medial lemniscus rotates 90 degrees at the pons. The secondary axons from neurons giving sensation to the head, stay at around the same place, while the leg axons move outwards.

The axons travel up the rest of the brainstem, and synapse at the thalamus (at the ventral posterolateral nucleus). Neurons starting in the thalamus travel up the posterior limb of the internal capsule, and again head and leg swap relative positions. The axons synapse in the primary sensory cortex, with lower body sensation most medial (e.g., the paracentral lobule) and upper body more lateral.

This page uses Creative Commons Licensed content from Wikipedia (view authors).

Around Wikia's network

Random Wiki