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The Positive and Negative Syndrome Scale or (PANSS) is a standard rating scale used for measuring symptom reduction of schizophrenia patients.

The scale has 30 items, each assessed on a seven-point scale from absent to extreme. It is divided into sub-scales covering both positive PANSS-P and negative symptoms PANSS-N.

It is widely used in the study of psychosis.

The name refers to the syndrome of positive symptoms, meaning those symptoms of disease that manifest as the presence of traits, and the syndrome of negative symptoms, meaning those symptoms that manifest as the absence of traits.

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Rating scale has averaged at 75 in most trials with those experiencing chronic schizophrenia.

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