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Pneumotaxic center

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The pneumotaxic center, also known as the pontine respiratory group (PRG), is a network of neurons in the rostral dorsal lateral pons. It consists of the Kölliker-Fuse nucleus and the medial parabrachial nucleus.[1]

Respiratory effects

The PRG antagonises the apneustic center, cyclically inhibiting inspiration. The PRG limits the burst of action potentials in the phrenic nerve, effectively decreasing the tidal volume and regulating the respiratory rate. Absence of the PRG results in an increase in depth of respiration and a decrease in respiratory rate.

External links


  1. Song G, Yu Y, Poon C (2006). Cytoarchitecture of pneumotaxic integration of respiratory and nonrespiratory information in the rat. J Neurosci 26 (1): 300–10.
  1. Levitzky, Michael G. (2002). Pulmonary Physiology, 6th edition, 193–4, McGraw-Hill Professional.
  2. Costanzo, Linda S. (2006). Physiology, 3rd edition, Philadelphia, PA: Elsevier.
  3. Roger Shannon, David M. Baekey, Kendall F. Morris, Sarah C. Nuding, Lauren S. Segers and Bruce G. Lindsey (2004). Pontine respiratory group neuron discharge is altered during fictive cough in the decerebrate cat. Respiratory Physiology & Neurobiology 142 (1): 43–54.

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