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The pneumotaxic center, also known as the pontine respiratory group (PRG), is a network of neurons in the rostral dorsal lateral pons. It consists of the Kölliker-Fuse nucleus and the medial parabrachial nucleus.
The PRG antagonises the apneustic center, cyclically inhibiting inspiration. The PRG limits the burst of action potentials in the phrenic nerve, effectively decreasing the tidal volume and regulating the respiratory rate. Absence of the PRG results in an increase in depth of respiration and a decrease in respiratory rate.
- Levitzky, Michael G. (2002). Pulmonary Physiology, 6th edition, 193–4, McGraw-Hill Professional.
- Costanzo, Linda S. (2006). Physiology, 3rd edition, Philadelphia, PA: Elsevier.
- Roger Shannon, David M. Baekey, Kendall F. Morris, Sarah C. Nuding, Lauren S. Segers and Bruce G. Lindsey (2004). Pontine respiratory group neuron discharge is altered during fictive cough in the decerebrate cat. Respiratory Physiology & Neurobiology 142 (1): 43–54.
Respiratory system, physiology: respiratory physiology
lung volumes - vital capacity - functional residual capacity - respiratory minute volume - closing capacity - dead space - spirometry - body plethysmography - peak flow meter - thoracic independent volume - bronchial challenge test
ventilation/perfusion ratio (V/Q) and scan - zones of the lung - gas exchange - pulmonary gas pressures - alveolar gas equation - hemoglobin - oxygen-haemoglobin dissociation curve (2,3-DPG, Bohr effect, Haldane effect) - carbonic anhydrase (chloride shift) - oxyhemoglobin - respiratory quotient - arterial blood gas - diffusion capacity - Dlco
|Control of respiration|
Human brain, rhombencephalon, metencephalon: pons (TA A14.1.05.101-604, GA 9.785)
| Other grey: Raphe/|
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