Phendimetrazine
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File:Phendimetrazine.png | |
| 3,4-Dimethyl-2-phenyl-morpholine IUPAC name | |
| CAS number 634-03-7 | ATC code [[ATC_code_|]][1] |
| PubChem 12460 | DrugBank [2] |
| Chemical formula | {{{chemical_formula}}} |
| Molecular weight | 191.27 |
| Bioavailability | Peak plasma levels occur within 1 to 3 hours. Absorption is usually complete by 4 to 6 hours |
| Metabolism | hepatic |
| Elimination half-life | 19-24 hours |
| Excretion | Urinary elimination |
| Pregnancy category | C (US) |
| Legal status | C-III (US) |
| Routes of administration | Oral |
| Indicated for: |
Phendimetrazine (Bontril®) is a weight loss medication. Phendimetrazine is chemically related to amphetamines and is a Schedule III drug under the Convention on Psychotropic Substances. In the United States, phendimetrazine is a Schedule III controlled substance under the Uniform Controlled Substances Act of 1970.
Phendimetrazine is used clinically in the form of phendimetrazine tartrate.
Approximately 30% of a given dose of phendimetrazine is metabolized into phenmetrazine, which may account for part of its anorectic effect, and probably also influences abuse potential; individuals who metabolise a greater proportion of phendimetrazine into phenmetrazine are more likely to develop problems with dependence and addiction.
According to the "List of psychotropic substances under international control," phendimetrazine is a Schedule IV controlled substance.[citation needed]
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| This page uses content from the English-language version of Wikipedia. The original article was at Phendimetrazine. The list of authors can be seen in the page history. As with Psychology Wiki, the text of Wikipedia is available under the GNU Free Documentation License. |
