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Peroxisomal disorders are a class of conditions which lead to disorders of lipid metabolism.
A deficiency in the protein import can lead to empty peroxisomes, leading to abnormalities in the brain, called Zellweger syndrome. A deficiency in the peroxin Pex2 has shown to be responsible for one form of the syndrome. A milder inherited disease is caused by a defective receptor for the N-terminal import signal. Deficiency of the formation of plasmalogens can also cause severe brain disorders, leading to neurological disease.
Other peroxisomal disordersEdit
Other examples of peroxisomal disorders include: