Pedunculopontine nucleus
From Psychology Wiki
Community portal · Tasks to do · News · Help
Clinical · Educational · Ind&Org · Other fields · Professional · Transpersonal · World
Assessment |
Biopsychology |
Comparative |
Cognitive |
Developmental |
Language
Personality |
Philosophy |
Research Methods |
Social |
Statistics
Biological: Behavioural genetics · Evolutionary psychology · Neuroanatomy · Neurochemistry · Neuroendocrinology · Psychoneuroimmunology · Physiological Psychology · Psychopharmacology
The pedunculopontine nucleus (PPN) (or pedunculopontine tegmental nucleus) is located in the brainstem, caudal to the substantia nigra and adjacent to the superior cerebellar peduncle. It is composed by a wide variety of neurochemical cell types, including cholinergic, glutamatergic and GABAergic cells. The PPN has been classically considered as one of the main components of the reticular activating system.
One of the distinctive characteristics of the PPN is the wide range of its projections. PPN neurons send their axons to several targets in the thalamus, basal ganglia, cerebral cortex, basal forebrain, and lower brainstem. A particularly interesting area for the study of PPN projections is the basal ganglia, due to the high level of interconnectivity between them. Indeed, both share many characteristics in terms of projection targets and functions.
The PPN is involved in many functions, including arousal, attention, learning, reward, and locomotion. It is also implicated in the generation and maintenance of REM sleep.
[edit] External links
| This page uses content from the English-language version of Wikipedia. The original article was at Pedunculopontine nucleus. The list of authors can be seen in the page history. As with Psychology Wiki, the text of Wikipedia is available under the GNU Free Documentation License. |
