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Pargyline chemical structure
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|Molecular weight||159.23 g/mol|
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It functions by inhibiting the metabolism of catecholamines and tyramine within presynaptic nerve terminals. Patients taking pargyline must avoid concurrent consumption of tyramine-containing foods such as blue cheese and beer, as this can lead to a hypertensive crisis.
- ↑ Murphy DL, Karoum F, Pickar D, et al (1998). Differential trace amine alterations in individuals receiving acetylenic inhibitors of MAO-A (clorgyline) or MAO-B (selegiline and pargyline). J. Neural Transm. Suppl. 52: 39–48.
- ↑ Fuentes JA, Ordaz A, Neff NH (July 1979). Central mediation of the antihypertensive effect of pargyline in spontaneously hypertensive rats. Eur. J. Pharmacol. 57 (1): 21–7.
- ↑ Tulane University School of Medicine Department of Pharmacology: Autonomic Drug Profile handout, October 2006
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