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The palmomental reflex (PMR) is an example of a primitive reflex. As such it is present in infancy, disappears during maturation of the brain during childhood but may reappear due to processes that disrupt the normal cortical inhibitory pathways.
Marinesco and Radivici in their seminal paper hypothesize that both the afferent (receptive) and efferent (motor) arms of the reflex are on the same side (ipsilateral) to the hand stimulated; however this hypothesis remains unsubstantiated.
The PMR has been found to be present more frequently in various neurological conditions both localized and diffuse. These include congenital conditions such as Down's syndrome where it is unclear whether the reflex persists throughout life or disappears and then re-appears in association with the onset of Alzheimer's disease pathology. The reflex is common in the elderly population and should not be taken as indicative of a dementing process.
Eliciting and Observing responseEdit
The thenar eminence is stroked briskly with a thin stick, from proximal(edge of wrist) to distal (base of thumb) using moderate pressure. A positive response is considered if there is a single visible twitch of the ipsilateral mentalis muscle (chin muscle on the same side as the hand tested).
A study set in a neurosurgical in-patient population showed there is no significant association between the side of the reflex and the side of the hemispheric lesion in patients with unilateral (one-sided) reflexes and unilateral (one-sided) lesions.
- ↑ Marinesco G, Radovici A (1920). Sur un reflexe cutane nouveau: reflexe palmo-mentonnier. Rev Neurol 27: 237-40.
- ↑ 2.0 2.1 2.2 2.3 Owen G, Mulley GP (2002). The palmomental reflex: a useful clinical sign?. J. Neurol. Neurosurg. Psychiatr. 73 (2): 113–5.
- ↑ Gotkine M, Haggiag S, Abramsky O, Biran I (2005). Lack of hemispheric localizing value of the palmomental reflex. Neurology 64 (9): 1656.
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