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.Oxytocin may play a role in the amelioration of autism and may be an effective autism therapy for repetitive and affiliative behaviors;[1] two related studies in adults found that oxytocin decreased repetitive behaviors and improved interpretation of emotions, but these preliminary results do not necessarily apply to children.[2] An experimental drug STX107 has stopped overproduction of metabotropic glutamate receptor 5 in rodents, and it has been hypothesized that this may help in about 5% of autism cases, but this hypothesis has not been tested in humans.[2]

The Center of Cognitive Neuroscience in Lyon, France concluded that oxytocin may help reduce the negative symptoms of autism.[3]

Gordon et al (2013) reported that intranasal administration of oxytocin appeared to significantly increased appropriate brain activity to social stimuli an a sample of 17 children with high-functioning autism spectrum disorder. Its administration may help to improve the effectiveness of social skills training in this group of people [1]


  1. Bartz JA, Hollander E (2008). Oxytocin and experimental therapeutics in autism spectrum disorders. Prog Brain Res 170 (451–62): 451.
  2. 2.0 2.1 Opar A (2008). Search for potential autism treatments turns to 'trust hormone'. Nat Med 14 (4): 353.
  3. includeonly>""Love" hormone may help autism symptoms", Reuters, 2010-02-17.

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