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Oxotremorine

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Oxotremorine chemical structure
Oxotremorine

1-(4-Pyrrolidin-1-ylbut-2-yn-1-yl)pyrrolidin-2-one
IUPAC name
CAS number
70-22-4
ATC code

none[1]

PubChem
[2]
DrugBank
[3]
Chemical formula {{{chemical_formula}}}
Molecular weight 206.28
Bioavailability
Metabolism
Elimination half-life
Excretion
Pregnancy category C
Legal status {{{legal_status}}}
Routes of administration Oral, intravenous


Oxotremorine is a parasympathomimetic drug that acts as a non-selective muscarinic acetylcholine receptor agonist.[1]

Oxotremorine produces ataxia, tremor and spasticity, similar to those symptoms seen in Parkinsonism, and has thus become a research tool in experimental studies aimed at determining more effective anti-Parkinsonian drugs.[2]

References Edit

  1. Tang C, Castoldi AF, Costa LG (April 1993). Effects of the muscarinic agonist oxotremorine on membrane fluidity in rat lymphocytes. Biochem. Mol. Biol. Int. 29 (6): 1047–54.
  2. Craig, C. R.; Stitzel, R. E. (2004). Modern Pharmacology, Boston: Little, Brown.

See also Edit


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