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Oxazepam

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File:Oxazepam.png
Oxazepam

9-chloro-4-hydroxy-6-phenyl- 2,5-diazabicyclo[5.4.0] undeca-5,8,10,12-tetraen-3-one
IUPAC name
CAS number
604-75-1
ATC code

N05BA04

PubChem
4616
DrugBank
APRD00676
Chemical formula C15H11ClN2O2
Molecular weight 286.71
Bioavailability  ?
Metabolism Hepatic
Elimination half-life 4-15 hours
Excretion Renal
Pregnancy category  ?
Legal status Schedule IV(US)
Routes of administration Oral

Oxazepam (marketed under brand names Alepam®, Murelax®, Serax®, Serepax®, Seresta®) is a drug which is a benzodiazepine derivative. It possesses anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties.

Contents

[edit] Pharmacology

See Diazepam#Pharmacology. Oxazepam is also a metabolic by-product of diazepam.

[edit] Indications

It is an intermediate acting benzodiazepine with a slow onset of action, so it is usually prescribed to individuals who have trouble staying asleep, rather than falling asleep. It is commonly prescribed for anxiety disorders with associated tension, irritability, and agitation. It is also prescribed for drug and alcohol withdrawal, and for anxiety associated with depression.

[edit] Dosage

  • Mild/moderate anxiety - 10 to 15mg, 3 to 4 times daily
  • Severe anxiety - 15 to 30mg, 3 to 4 times daily
  • Symptoms related to alcohol withdrawl - 15 to 30mg, 3 to 4 times daily

[edit] Side Effects

See Diazepam#Side_Effects.

[edit] Interactions

See Diazepam#Interactions.

[edit] Contraindications

See Diazepam#Contraindications.

[edit] Overdose

See Diazepam#Overdose.

[edit] Legal Status

Oxazepam is a Schedule IV drug under the Convention on Psychotropic Substances [1].

[edit] External links


Benzodiazepines edit

{Diazepam} {Oxazepam} {Nitrazepam} {Temazepam} {Lorazepam} {Flunitrazepam} {Bromazepam} {Clobazam} {Clonazepam} {Chlordiazepoxide} {Triazolam} {Midazolam} {Alprazolam} {Estazolam} {Quazepam} {Clorazepate} {Medazepam} {Prazepam} {Flurazepam} {Nordazepam}

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