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An opioid antagonist is an receptor antagonist that acts on opioid receptors.

Naloxone and naltrexone are opioid antagonist drugs which are competitive antagonists that bind to the opioid receptors with higher affinity than agonists but do not activate the receptors. This effectively blocks the receptor, preventing our systems from making use of opiates and endorphins.

See alsoEdit

• Opioid
• Buprenorphine, an opioid with both partial agonist and antagonist actions

External linksEdit

• David S, Lancaster T, Stead LF. Opioid antagonists for smoking cessation (Cochrane Review), The Cochrane Library, Issue 2, 2005. Chichester, UK: John Wiley & Sons, Ltd.
• MeSH Opioid+Antagonists