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An '''opioid antagonist''' is an [[receptor antagonist]] that acts on [[opioid receptor]]s. |
An '''opioid antagonist''' is an [[receptor antagonist]] that acts on [[opioid receptor]]s. |
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| − | [[Naloxone]] and [[naltrexone]] are opioid antagonist drugs which are [[competitive antagonist]]s that bind to the opioid receptors with higher affinity than agonists but do not activate the receptors. This effectively blocks the receptor, preventing our systems from making use of opiates and endorphins. |
+ | [[Naloxone]] and [[naltrexone]] are opioid antagonist drugs which are [[competitive antagonist]]s that bind to the opioid receptors with higher affinity than agonists but do not activate the receptors. This effectively blocks the receptor, preventing our systems from making use of [[opiates]] and [[endorphins]]. |
==See also== |
==See also== |
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Revision as of 08:42, 16 January 2008
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An opioid antagonist is an receptor antagonist that acts on opioid receptors.
Naloxone and naltrexone are opioid antagonist drugs which are competitive antagonists that bind to the opioid receptors with higher affinity than agonists but do not activate the receptors. This effectively blocks the receptor, preventing our systems from making use of opiates and endorphins.
See also
- Opioid
- Buprenorphine, an opioid with both partial agonist and antagonist actions
External links
- David S, Lancaster T, Stead LF. Opioid antagonists for smoking cessation (Cochrane Review), The Cochrane Library, Issue 2, 2005. Chichester, UK: John Wiley & Sons, Ltd.
- MeSH Opioid+Antagonists
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