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In genetics, non-coding DNA describes DNA which does not contain instructions for making proteins (or other cell products such as RNAs). In eukaryotes, a large percentage of many organisms' total genome sizes are comprised of noncoding DNA (a puzzle known as the "C-value enigma"). Some noncoding DNA is involved in regulating the activity of coding regions. However, much of this DNA has no known function and is sometimes referred to as "junk DNA".
Recent evidence suggests that "junk DNA" may in fact be employed by proteins created from coding DNA. An experiment concerning the relationship between introns and coded proteins provided evidence for a theory that "junk DNA" is just as important as coding DNA. This experiment consisted of damaging a portion of noncoding DNA in a plant which resulted in a significant change in the leaf structure because structural proteins depended on information contained in introns.
- Eukaryotic chromosome fine structure
- Genetic code
- Junk DNA
- Regulatory sequence
- Bennett, M.D. and I.J. Leitch (2005). "Genome size evolution in plants" T.R. Gregory (ed.) The Evolution of the Genome, 89-162, San Diego: Elsevier.
- Gregory, T.R (2005). "Genome size evolution in animals" T.R. Gregory (ed.) The Evolution of the Genome, San Diego: Elsevier.
- Animal Genome Size Database
- Plant DNA C-values Database
- Fungal Genome Size Database
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