Nicotinic agonist
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A nicotinic agonist is a drug which enhances the action at the nicotinic acetylcholine receptor.
Examples include:
- nicotine (by definition -- the "nicotinic acetylcholine receptor" is named for its affinity for nicotine)
- epibatidine
- lobeline
- varenicline
| Agonist | Receptor preference[1] | Mechanism[1] | Clinical use[1] |
|---|---|---|---|
| nicotine | stimulation | tobacco smoking cessation | |
| lobeline |
| stimulation | |
| epibatidine | stimulation | none | |
| suxamethonium | Muscle type | depolarization block | muscle relaxant |
| decamethonium | Muscle type | depolarization block | none |
| varenicline | α4β2 | partial agonist | tobacco smoking cessation [2] |
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