Neuromedin B receptor
Talk0this wiki
Assessment |
Biopsychology |
Comparative |
Cognitive |
Developmental |
Language |
Individual differences |
Personality |
Philosophy |
Social |
Methods |
Statistics |
Clinical |
Educational |
Industrial |
Professional items |
World psychology |
Biological: Behavioural genetics · Evolutionary psychology · Neuroanatomy · Neurochemistry · Neuroendocrinology · Psychoneuroimmunology · Physiological Psychology · Psychopharmacology
| edit |
The neuromedin B receptor (NMBR), now known as BB1 [1] is a G protein-coupled receptor whose endogenous ligand is neuromedin B.[2] is on of the neuromedin receptors.
Neuromedin B receptor binds neuromedin B, a potent mitogen and growth factor for normal and neoplastic lung and for gastrointestinal epithelial tissue.[3]
Contents |
See also
Edit
ReferencesEdit
- ↑ Bombesin Receptors: BB1. IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology.
- ↑ Benya RV, Kusui T, Pradhan TK, Battey JF, Jensen RT (1995). Expression and characterization of cloned human bombesin receptors. Mol. Pharmacol. 47 (1): 10–20.
- ↑ Entrez Gene: NMBR neuromedin B receptor.
Further readingEdit
- Corjay MH, Dobrzanski DJ, Way JM, et al. (1991). Two distinct bombesin receptor subtypes are expressed and functional in human lung carcinoma cells.. J. Biol. Chem. 266 (28): 18771–9.
- Wu JM, Hoang DO, Feldman RI (1995). Differential activation of human gastrin-releasing peptide receptor-mediated responses by bombesin analogs.. Mol. Pharmacol. 47 (4): 871–81.
- Benya RV, Kusui T, Pradhan TK, et al. (1995). Expression and characterization of cloned human bombesin receptors.. Mol. Pharmacol. 47 (1): 10–20.
- Bitar KN, Zhu XX (1994). Expression of bombesin-receptor subtypes and their differential regulation of colonic smooth muscle contraction.. Gastroenterology 105 (6): 1672–80.
- Giladi E, Nagalla SR, Spindel ER (1993). Molecular cloning and characterization of receptors for the mammalian bombesin-like peptides.. J. Mol. Neurosci. 4 (1): 41–54.
- Fathi Z, Benya RV, Shapira H, et al. (1993). The fifth transmembrane segment of the neuromedin B receptor is critical for high affinity neuromedin B binding.. J. Biol. Chem. 268 (20): 14622–6.
- Kane MA, Toi-Scott M, Johnson GL, et al. (1996). Bombesin-like peptide receptors in human bronchial epithelial cells.. Peptides 17 (1): 111–8.
- Sainz E, Akeson M, Mantey SA, et al. (1998). Four amino acid residues are critical for high affinity binding of neuromedin B to the neuromedin B receptor.. J. Biol. Chem. 273 (26): 15927–32.
- Lee S, Kim Y (1999). Solution structure of neuromedin B by (1)H nuclear magnetic resonance spectroscopy.. FEBS Lett. 460 (2): 263–9.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903.
- Matusiak D, Glover S, Nathaniel R, et al. (2005). Neuromedin B and its receptor are mitogens in both normal and malignant epithelial cells lining the colon.. Am. J. Physiol. Gastrointest. Liver Physiol. 288 (4): G718–28.
External linksEdit
- Bombesin Receptors: BB1. IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology.
- MeSH Receptors,+Bombesin
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
| This page uses Creative Commons Licensed content from Wikipedia (view authors). |
