Wikia

Psychology Wiki

Changes: Neurofibrillary tangles

Edit

Back to page

 
(delete medsign stub)
 
Line 2: Line 2:
 
'''Neurofibrillary tangles''' are pathological [[protein]] aggregates found within [[neuron]]s in cases of [[Alzheimer's disease]]. Tangles are formed by [[phosphorylation|hyperphosphorylation]] of a [[microtubule]]-associated protein known as [[tau (protein)|tau]], causing it to aggregate in an insoluble form. The precise mechanism of tangle formation is not completely understood, and it is still controversial whether tangles are a primary causative factor in the disease or play a more peripheral role.
 
'''Neurofibrillary tangles''' are pathological [[protein]] aggregates found within [[neuron]]s in cases of [[Alzheimer's disease]]. Tangles are formed by [[phosphorylation|hyperphosphorylation]] of a [[microtubule]]-associated protein known as [[tau (protein)|tau]], causing it to aggregate in an insoluble form. The precise mechanism of tangle formation is not completely understood, and it is still controversial whether tangles are a primary causative factor in the disease or play a more peripheral role.
   
{{Medsign-stub}}
+
 
[[Category:Medical signs]]
 
[[Category:Medical signs]]
 
[[Category:Neurology]]
 
[[Category:Neurology]]

Latest revision as of 10:48, June 11, 2006

Assessment | Biopsychology | Comparative | Cognitive | Developmental | Language | Individual differences | Personality | Philosophy | Social |
Methods | Statistics | Clinical | Educational | Industrial | Professional items | World psychology |

Biological: Behavioural genetics · Evolutionary psychology · Neuroanatomy · Neurochemistry · Neuroendocrinology · Neuroscience · Psychoneuroimmunology · Physiological Psychology · Psychopharmacology (Index, Outline)


Neurofibrillary tangles are pathological protein aggregates found within neurons in cases of Alzheimer's disease. Tangles are formed by hyperphosphorylation of a microtubule-associated protein known as tau, causing it to aggregate in an insoluble form. The precise mechanism of tangle formation is not completely understood, and it is still controversial whether tangles are a primary causative factor in the disease or play a more peripheral role.

This page uses Creative Commons Licensed content from Wikipedia (view authors).

Around Wikia's network

Random Wiki