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Neonatal abstinence syndrome (NAS) is a withdrawal syndrome of infants, caused by administration of drugs. There are two types of NAS, prenatal and postnatal. Prenatal NAS is caused by substance abuse by the mother, while postnatal NAS is caused by discontinuation of drugs directly to the infant.[1]

The drugs involved are e.g. opioids, selective serotonin reuptake inhibitors (SSRIs), alcoholic beverages and benzodiazepines.[1][2]

Clinical presentationEdit

The syndrome is characterized by irritability, excessive loud crying, tremors a voracious appetite but with no weight gain.


Evidence indicates that the condition can lead to reduced attention span[citation needed] and hyperactivity[citation needed] later in childhood.

See alsoEdit

  • [Drug withdrawal]]


  1. 1.0 1.1 - Neonatal Abstinence Syndrome Author: Jaques Belik, MD
  2. Iqbal MM, Sobhan T, Ryals T (January 2002). Effects of commonly used benzodiazepines on the fetus, the neonate, and the nursing infant. Psychiatric Services 53 (1): 39–49.

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