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Myalgia means " muscle pain" and is a symptom of many diseases and disorders. The most common causes are the overuse or over-stretching of a muscle or group of muscles. Myalgia without a traumatic history is often due to viral infections. Longer-term myalgias may be indicative of a metabolic myopathy, some nutritional deficiencies or chronic fatigue syndrome.
The most common causes of myalgia are overuse,
injury or strain. However, myalgia can also be caused by diseases, disorders, medications, or as a response to a vaccination. It is also a sign of acute rejection after heart transplant surgery.
The most common causes are:
Injury or trauma, including sprains, hematoma
Overuse: using a muscle too much, too often, including protecting a separate injury
Muscle pain occurs with:
Overuse of a muscle is using it too much, too soon and/or too often.
The most common causes of myalgia by
injury are: sprains and strain (injury).
Multiple sclerosis(neurologic pain interpreted as muscular), Myalgic Encephalomyelitis, Myositis, Lupus erythematosus, Familial Mediterranean fever, Polyarteritis nodosa, Devic's disease, Morphea
Metabolic defect Edit
Carnitine palmitoyltransferase II deficiency, Conn's syndrome, Adrenal insufficiency, Hyperthyroidism,
Chronic fatigue syndrome, Ehlers Danlos Syndrome, Hypokalemia, Exercise intolerance, Mastocytosis, Peripheral neuropathy, Eosinophilia myalgia syndrome, Fibromyalgia, Barcoo Fever, Herpes, Delayed onset muscle soreness, AIDS, HIV, Tumor-induced osteomalacia, Post Orgasmic Illness Syndrome
Acrylamide, Aspirin, colesevelam, darbepoetin, darunavir, daptomycin, ezetimibe, ibandronate sodium, ibuprofen, imiquimod, interferons, isotretinoin, procainamide, quinupristin/dalfopristin, statins, sumatriptan, tasigna, tiotropium, vardenafil, zolmitriptan, zocor.
Withdrawal syndromes Edit
Sudden cessation of
high-dose corticosteroids, opioids, barbiturates, benzodiazepines, or alcohol can induce myalgia.
External links Edit
Pain and nociception
Head and neck
Jaw and mouth ( Odynophagia ) • Ear ( otalgia, otitis media, otitis externa) • Eye ( glaucoma) • Head ( headache, migraine, tension headache, cluster headache, cerebral aneurysm, sinusitis, meningitis) • Neck (atypical myocardial infarction)
Back ( upper back, lower back, spinal disc herniation, degenerative disc disease, coccydynia) • Breast ( perimenstrual, breast cancer) • Chest ( myocardial infarction, gastroesophageal reflux disease, pancreatitis, hiatus hernia, aortic dissection, asymptomatic pulmonary embolism, Tietze's syndrome) • Shoulder (right side - cholecystitis)
right upper quadrant ( peptic ulcer disease, gastroenteritis, hepatitis, pancreatitis, cholecystitis, atypical myocardial infarction, abdominal aortic aneurysm, asymptomatic gastric cancer) • Left and right lower quadrant ( appendicitis, ulcerative colitis, Crohn's disease, ectopic pregnancy, endometriosis, pelvic inflammatory disease, diverticulitis, urolithiasis, pyelonephritis, colorectal cancer)
Arm ( myocardial infarction, left arm) • Leg ( deep vein thrombosis, peripheral artery occlusive disease, claudication, spinal disc herniation, sciatica)
Joints ( arthralgia)
Small joints (
osteoarthritis, rheumatoid arthritis, systemic lupus erythematosis, gout, pseudogout • Large joints ( osteoarthritis, septic arthritis, hemarthrosis, osteonecrosis) • Back joints ( ankylosing spondylitis, inflammatory bowel disease) • Other ( psoriatic arthritis, Reiter's syndrome)
Delayed onset muscle soreness, myalgia, physical trauma
cold pressor test, congenital insensitivity to pain, dolorimeter, HSAN ( Type I, II congenital sensory neuropathy, III familial dysautonomia, IV congenital insensitivity to pain with anhidrosis, V congenital insensitivity to pain with partial anhidrosis), neuralgia, pain asymbolia, pain disorder, paroxysmal extreme pain disorder • Allodynia, breakthrough pain, chronic pain, hyperalgesia, hypoalgesia, hyperpathia, phantom pain, referred pain
Anterolateral system, gate control theory of pain, pain management ( anesthesia, cordotomy), pain scale, pain threshold, pain tolerance, posteromarginal nucleus, substance P, suffering, OPQRST