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Molindone

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Molindone chemical structure
Molindone

3-ethyl-2-methyl-5-(morpholin-4-ylmethyl)-
1,5,6,7-tetrahydro-4H-indol-4-one
IUPAC name
CAS number
7416-34-4
ATC code

N05AE02

PubChem
23897
DrugBank
[1]
Chemical formula {{{chemical_formula}}}
Molecular weight 276.374 g/mol
Bioavailability
Metabolism Hepatic
Elimination half-life 1.5 hours
Excretion Minor, renal and fecal
Pregnancy category
Legal status
Routes of administration Oral

Molindone is a therapeutic antipsychotic, used in the treatment of schizophrenia.[1] It works by blocking the effects of dopamine in the brain, leading to diminished psychoses. It is rapidly absorbed when taken by mouth.

Molindone is sold under the product name Moban.

Adverse effects

Main article: Typical antipsychotic

The side effect profile of molindone is similar to that of other typical antipsychotics. Unlike most antipsychotics, however, molindone use is associated with weight loss.[2][3]

See also

References

  1. molindone. (web) F.A. Davis Company. URL accessed on 2007-11-04.
  2. Bagnall A, Fenton M, Kleijnen J, Lewis R (2007). Molindone for schizophrenia and severe mental illness. Cochrane Database Syst Rev (1): CD002083.
  3. Allison DB, Mentore JL, Heo M, et al (1999). Antipsychotic-induced weight gain: a comprehensive research synthesis. Am J Psychiatry 156 (11): 1686–96. Free full text


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