Methocarbamol
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Methocarbamol chemical structure | |
| [2-hydroxy-3-(2-methoxyphenoxy)-propyl] aminoformate IUPAC name | |
| CAS number 532-03-6 | ATC code |
| PubChem 4107 | DrugBank APRD01102 |
| Chemical formula | {{{chemical_formula}}} |
| Molecular weight | 241.241 g/mol |
| Bioavailability | |
| Metabolism | Hepatic |
| Elimination half-life | 1.14-1.24 hours[1] |
| Excretion | {{{excretion}}} |
| Pregnancy category | |
| Legal status | |
| Routes of administration | Oral, intravenous |
Methocarbamol is a central muscle relaxant for skeletal muscles, used to treat spasms. Robaxin, Robaxacet, and Robax Platinum are trade names for methocarbamol. It is structurally related to guaifenesin, and produces guaifenisin in the body as a metabolite.
References and End Notes
Edit
- Methocarbamol The Elephant Formulary
- Alphabetical Listing of ATC drugs and codes (PDF) mSupply, by Sustainable Solutions. Katmandu, Nepal.
- ^ Sica DA, Comstock TJ, Davis J, Manning L, Powell R, Melikian A, Wright G. "Pharmacokinetics and protein binding of methocarbamol in renal insufficiency and normals." European Journal of Clinical Pharmacology. 1990;39(2):193-4. PMID 2253675
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External linksEdit
Muscle relaxants (M03) | |
|---|---|
| Peripherally acting (primarily antinicotinic, neuromuscular-blocking drugs) |
curare alkaloids (Alcuronium, Dimethyltubocurarine, Tubocurarine) - choline derivatives (Suxamethonium) - other quaternary ammonium compounds (Atracurium, Cisatracurium, Doxacurium chloride, Fazadinium bromide, Gallamine, Hexafluronium, Mivacurium chloride, Pancuronium, Pipecuronium bromide, Rocuronium bromide, Vecuronium) - other (Botulinum toxin) |
| Centrally acting |
carbamic acid esters (Phenprobamate, Carisoprodol, Methocarbamol, Styramate, Febarbamate), Baclofen, Chlormezanone, Chlorzoxazone, Cyclobenzaprine, Lorazepam, Mephenesin, Orphenadrine, Phenyramidol, Pridinol, Tetrazepam, Thiocolchicoside, Tizanidine, Tolperisone |
| Directly acting | |
| This page uses Creative Commons Licensed content from Wikipedia (view authors). |
