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Mesoridazine

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Mesoridazine chemical structure
Mesoridazine

10-{2-[(RS)1-Methylpiperidin-2-yl]ethyl}-2-methylsulfinyl-10H-phenothiazine
IUPAC name
CAS number
5588-33-0
ATC code

N05AC03

PubChem
4078
DrugBank
APRD00610
Chemical formula {{{chemical_formula}}}
Molecular weight 386.576 g/mol
Bioavailability
Metabolism Hepatic/Renal
Elimination half-life 24 to 48 hours
Excretion Biliary/Renal
Pregnancy category C (USA)
Legal status Rx-only
Routes of administration oral, intravenous

Mesoridazine besylate (trade name Serentil) is a neuroleptic drug that is used in the treatment of schizophrenia, organic brain disorders, psychoneuroses, and alcoholism. It is the besylate salt of a metabolite of thioridazine. It exerts its actions through a central adrenergic-blocking, a dopamine-blocking, a serotonin-blocking, and a weak anticholinergic action. It also exerts part of its actions through depression of hypothalamic centers, like other phenothiazines.

It was withdrawn from the United States market in 2004.

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