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Image:Melperone skeletal.svg Melperone
1-(4-fluorophenyl)-4-(4-methyl-1-piperidyl)butan-1-one IUPAC name
CAS number 3575-80-2	ATC code N05AD03
PubChem 15387	DrugBank [1]
Chemical formula	{{{chemical_formula}}}
Molecular weight	263.35 g/mol
Bioavailability
Metabolism	Hepatic (inhibits CYP2D6[1])
Elimination half-life	3–4 hours (oral) 6 hours (IM)
Excretion
Pregnancy category
Legal status
Routes of administration	Oral, intramuscular injection

Melperone (INN, also known as methylperone) is a butyrophenone atypical antipsychotic. It is sold under the trade names Buronil, Burnil, and Eunerpan.

[edit] Chemistry

• Molecular Formula: C16H23ClFNO
• Molecular Weight: 299.82
• Chemical Class: Butyrophenone
• Pharmacological Class: Atypical antipsychotic
• Appearance: White, crystalline odorless powder
• Solubility: Free soluble in water. Freely soluble in ethanol 99.5% and chloroform. Practically insoluble in diethyl ether.
• Melting Point: 205-210C
• pH (1% in water): 4.5-6.5
• Stability: 48 months

It is a white crystalline powder that is manufactured by Dupont Chemoswed (Sweden). It is a butyrophenone (1-(4-Fluorophenyl)-4-(4-methyl-1-piperidinyl)-1-butanone hydrochloride).

[edit] References

[edit] External links

• PubChem Substance
• ClinicalTrials.gov NCT00125138

This box: view • talk • edit Psycholeptics: antipsychotics (N05A)
Phenothiazine typical antipsychotics	Chlorpromazine • Fluphenazine • Mesoridazine • Perphenazine • Prochlorperazine • Promazine • Thioridazine/Sulforidazine • Trifluoperazine
Other typical antipsychotics	Indoles (Molindone) • Butyrophenones (Azaperone, Benperidol, Droperidol, Haloperidol) • Thioxanthenes (Flupentixol, Chlorprothixene, Thiothixene, Zuclopenthixol) • diphenylbutylpiperidines (Fluspirilene, Penfluridol, Pimozide) • other (Loxapine)
Atypical antipsychotics	Butyrophenones (Melperone) • Indoles (Sertindole, Ziprasidone) • Benzamides (Sulpiride, Remoxipride, Amisulpride) • diazepines/oxazepines/thiazepines (Clozapine, Olanzapine, Quetiapine) • other (Aripiprazole, Risperidone, Paliperidone, Zotepine)

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This page uses content from the English-language version of Wikipedia. The original article was at Melperone. The list of authors can be seen in the page history. As with Psychology Wiki, the text of Wikipedia is available under the GNU Free Documentation License.