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Melanocortin receptor

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melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
Symbol(s): MC1R
Locus: 16 q24.3
EC number [1]
EntrezGene 4157
OMIM 155555
RefSeq NM_002386
UniProt Q01726
melanocortin 2 receptor (adrenocorticotropic hormone)
Symbol(s): MC2R
Locus: 18 p11.2
EC number [2]
EntrezGene 4158
OMIM 607397
RefSeq NM_000529
UniProt Q01718
melanocortin 3 receptor
Symbol(s): MC3R
Locus: 20 q13.2 -13.3
EC number [3]
EntrezGene 4159
OMIM 155540
RefSeq NM_019888
UniProt P41968
melanocortin 4 receptor
Symbol(s): MC4R
Locus: 18 q22
EC number [4]
EntrezGene 4160
OMIM 155541
RefSeq NM_005912
UniProt P32245
melanocortin 5 receptor
Symbol(s): MC5R
Locus: 18 p11.2
EC number [5]
EntrezGene 4161
OMIM 600042
RefSeq NM_005913
UniProt P33032

Melanocortin receptors are members of the rhodopsin family of 7-transmembrane, G-protein coupled receptors.

There are five members of the melanocortin receptor system each with differing specificities for melanocortins.

MC2 is also known as the ACTH or corticotropin receptor because it is specific for ACTH alone.

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