Median raphe nucleus

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Brain: Median raphe nucleus
[[Image:|250px|center|]]
[[Image:|250px|center|]]
Latin	nucleus raphes medianus, nucleus centralis superior
Gray's	subject #
Part of
Components
Artery
Vein
BrainInfo/UW	hier-557
MeSH	[1]

The median raphe nucleus (or superior central nucleus) is composed of polygonal, fusiform and pyriform neurons and exists rostral to the nucleus raphe pontis.

One trait of the NCS is its inhibition by lysergic acid diethylamide and psilocin, two serotonin antagonist hallucinogens. The inactivation of the nucleus centralis superior via LSD produces a dose dependent inactivation in the NCS, but not in the raphe pallidus.

The free-moving cats, in which this was discovered, exhibited dose dependent behavioral changes when researched by Dr. Michael Trulson of the neurology department at Texas A&M University Medical School. ^[1].

[edit] See also

• Raphe nuclei

[edit] References

1. ↑ Trulson, M.E., Preussler DW and Trulson V.M. Differential effects of hallucinogenic drugs on the activity of serotonin-containing neurons in the nucleus centralis superior and nucleus raphe pallidus in free-moving cats. American Society for Pharmacology and Experimental Therapeutics Volume 228, Issue 1, pp. 94-102, 01/01/1984

v·d·e Brain: rhombencephalon (hindbrain)
Metencephalon/ pons	{| class="navbox collapsible nowraplinks" style="margin:auto; background:white;background:white;"
[[[:Template:Fullurl:Template:]] v]·[[[:Template:Fullurl:Template talk:]] d]·[[[:Template:Fullurl:Template:]] e]
Dorsal/ (tegmentum)	surface: Locus ceruleus Trigeminal lemniscus (Dorsal trigeminal tract, Ventral trigeminal tract) cranial nuclei: GSA: Principal V/Spinal V - VIII-c (Dorsal, Anterior)/VIII-v (Lateral, Superior, Medial, Inferior) - SVE: Motor V - VII - GSE: VI - GVE: VII: Superior salivary nucleus MLF, III, IV and VI (vestibulo-oculomotor fibers, medial vestibulospinal tract) sensory/ascending: Trapezoid body/VIII - Superior olivary nucleus Inferior cerebellar peduncle (Vestibulocerebellar tract) motor/descending: Apneustic center • Pneumotaxic center (Medial parabrachial nucleus) - Lateral parabrachial nucleus
Ventral/ (base)	Middle cerebellar peduncles (Pontocerebellar fibers) - Pontine nuclei motor/descending: Corticospinal tract - Corticobulbar tract - Corticopontine fibers
Raphe/reticular	Reticular formation (Caudal, Oral, Tegmental, Paramedian) • Raphe nuclei (Median)

|- style="white-space:nowrap;background:#ddddff;text-align:right;background-color: LightYellow" ! Myelencephalon/
medulla | colspan="1" style="text-align:left;width:100%;font-size:95%;background:#f7f7f7;" | {| class="navbox collapsible nowraplinks" style="margin:auto; background:white;background:white;" |- style="text-align:center;width:100%;"

!colspan="2" |

|- |- style="white-space:nowrap;background:#ddddff;text-align:right;padding-left:0em;padding-right:0em;background-color: LightYellow"

!

| colspan="1" style="text-align:left;width:100%;font-size:95%;" | surface: Posterior median sulcus - Postero-lateral sulcus - Area postrema

cranial nuclei: GVA: VII,IX,X: Solitary/tract • SVA: Gustatory nucleus • GSE: XII  • GVE: IX,X,XI: Ambiguus • SVE: X: Dorsal • IX: Inferior salivatory nucleus - MLF, III, IV and VI

sensory/ascending: Gracile nucleus • Cuneate nucleus (Accessory cuneate nucleus) • Sensory decussation  • Medial lemniscus

motor/descending: Dorsal respiratory group
|- style="white-space:nowrap;background:#ddddff;text-align:right;padding-left:0em;padding-right:0em;background-color: LightYellow"

!

| colspan="1" style="text-align:left;width:100%;font-size:95%;background:#f7f7f7;" | motor/descending: Ventral respiratory group - Pyramid (Motor decussation) - Inferior olivary nucleus (Olivocerebellar tract, Rubro-olivary tract)
surface: Anterior median fissure - Antero-lateral sulcus - Arcuate nucleus of medulla - Olivary body
|- style="white-space:nowrap;background:#ddddff;text-align:right;padding-left:0em;padding-right:0em;background-color: LightYellow"

!

| colspan="1" style="text-align:left;width:100%;font-size:95%;" | Reticular formation (Gigantocellular, Parvocellular, Ventral, Lateral, Paramedian) • Raphe nuclei (Obscurus, Magnus, Pallidus) |} |}

This page uses content from the English-language version of Wikipedia. The original article was at Median raphe nucleus. The list of authors can be seen in the page history. As with Psychology Wiki, the text of Wikipedia is available under the GNU Free Documentation License.