Wikia

Psychology Wiki

Medial forebrain bundle

Talk0
34,143pages on
this wiki
Revision as of 22:45, April 8, 2008 by Dr Joe Kiff (Talk | contribs)

Assessment | Biopsychology | Comparative | Cognitive | Developmental | Language | Individual differences | Personality | Philosophy | Social |
Methods | Statistics | Clinical | Educational | Industrial | Professional items | World psychology |

Biological: Behavioural genetics · Evolutionary psychology · Neuroanatomy · Neurochemistry · Neuroendocrinology · Neuroscience · Psychoneuroimmunology · Physiological Psychology · Psychopharmacology (Index, Outline)


Brain: Medial forebrain bundle
[[Image:|250px|center|]]
[[Image:|250px|center|]]
Latin fasciculus medialis telencephali
Gray's subject #
Part of
Components
Artery
Vein
BrainInfo/UW hier-416
MeSH [1]

The Medial forebrain bundle (MFB) is a bundle of the axon that carries information between the ventral tegmentum and the nucleus accumbens. This complex arrangment of nerve fibres arises from the basal olfactory regions of the brain as well as the periamygdaloid region and the septal nuclei and connects with the lateral preoptic area and other regions of the hypothalmus.


Role in brian stimulation reward

It is commonly accepted that the MFB is involved in the integration of reward and pleasure.

Electrical stimulation of the medial forebrain bundle is believed to cause sensations of pleasure. This hypothesis is based upon intracranial self-stimulation (ICSS) studies. Animals will work for MFB ICSS, and humans report that MFB ICSS is intensely pleasurable. This is most likely because the medial forebrain bundle carries information ventral tegmental area (VTA) to the nucleus accumbens (nAcc or Acb). The nAcc is a recognized reward center, and activation of the pathway from the VTA to the nAcc is believed to be rewarding.

See also

External links


This page uses Creative Commons Licensed content from Wikipedia (view authors).

Around Wikia's network

Random Wiki