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Medial dorsal nucleus

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Brain: Medial dorsal nucleus
Thalamic nuclei:
MNG = Midline nuclear group
AN = Anterior nuclear group
MD = Medial dorsal nucleus
VNG = Ventral nuclear group
VA = Ventral anterior nucleus
VL = Ventral lateral nucleus
VPL = Ventral posterolateral nucleus
VPM = Ventral posteromedial nucleus
LNG = Lateral nuclear group
PUL = Pulvinar
MTh = Metathalamus
LG = Lateral geniculate nucleus
MG = Medial geniculate nucleus
Latin nucleus mediodorsalis thalami
Gray's subject #
Part of
BrainInfo/UW hier-295
MeSH [1]

The medial dorsal nucleus (or dorsomedial nucleus) is a a large nucleus in the thalamus.

It communicates with the limbic lobe and prefrontal cortex. The connections of the medial dorsal nucleus have even been used to delineate the prefrontal cortex of the minipig.[1]

By stereology the number of brain cells in the region has been estimated to around 6.43 million neurons in the adult human brain and 36.3 million glial cells, and with the newborn having quite different numbers: around 11.2 million neurons and 10.6 million glial cells.[2]


The Medial dorsal nucleus has been implicated in memory. [3]

Clinical significance

It is one of the areas damaged in Korsakoff's syndrome in which Anterograde amnesia is a feature.[4]

Additional images

External links

  • Yamamoto T, Yoshida K, Yoshikawa H, Kishimoto Y, Oka H (1992). The medial dorsal nucleus is one of the thalamic relays of the cerebellocerebral responses to the frontal association cortex in the monkey: horseradish peroxidase and fluorescent dye double staining study. Brain Res 579 (2): 315-20. PMID 1378349.
  1. Jacob Jelsing, Anders Hay-Schmidt, Tim Dyrby, Ralf Hemmingsen, Harry B. M. Uylings, Bente Pakkenberg (2006). The prefrontal cortex in the Göttingen minipig brain defined by neural projection criteria and cytoarchitecture. Brain Research Bulletin 70 (4–6): 322–336.
  2. Maja Abitz, Rune Damgaard Nielsen, Edward G. Jones, Henning Laursen, Niels Graem and Bente Pakkenberg (2007). Excess of Neurons in the Human Newborn Mediodorsal Thalamus Compared with That of the Adult. Cerebral Cortex 17 (11): 2573–2578.
  3. *Reber, A.S & Reber, E.S. (2001). Dictionary of Psychology. London. Penguin
  4. *Reber, A.S & Reber, E.S. (2001). Dictionary of Psychology. London. Penguin

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