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| − | {{Biopsy}} |
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| − | {{Infobox Embryology | |
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| − | Name = {{PAGENAME}} | |
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| − | Latin = d. paramesonephricus | |
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| − | GraySubject = 252 | |
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| − | GrayPage = 1206 | |
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| − | Image = Gray1109.png | |
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| − | Caption = [[Urogenital sinus]] of female human [[embryo]] of eight and a half to nine weeks old. | |
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| − | Image2 = Gray993.png | |
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| − | Caption2 = Tail end of human embryo, from eight and a half to nine weeks old. | |
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| − | System = | |
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| − | CarnegieStage = 17 | |
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| − | Precursor = [[Intermediate mesoderm]] | |
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| − | GivesRiseTo = | |
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| − | MeshName = Mullerian+Ducts | |
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| − | MeshNumber = A16.254.570 | |
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| − | DorlandsPre = d_29 | |
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| − | DorlandsSuf = 12315002 | |
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| − | }} |
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| − | The '''Müllerian ducts''' (or '''paramesonephric ducts''') are paired ducts of the [[embryo]] which run down the lateral sides of the [[urogenital ridge]] and terminate at the [[mullerian tubercle| mullerian eminence]] in the primitive urogenital sinus. In the female, it will develop to form the fallopian tubes, uterus, and the upper portion of the vagina. It is tissue of [[mesoderm|mesodermal ]] origin. |
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| − | ==Development== |
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| − | [[Image:Gray1110.png|thumb|left|200px|Müllerian duct (blue) develops in females (middle image) and degenerates in males (bottom).]] |
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| − | Müllerian duct develops in females and degenerates in males. |
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| − | ==Regulation of development== |
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| − | The development of the Müllerian ducts is controlled by the presence or absence of "AMH", or [[Anti-müllerian hormone]] (also known as "MIF" for "Müllerian inhibiting factor", or "MIH" for "Müllerian inhibiting hormone"). |
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| − | {| class="wikitable" |
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| − | | male embryogenesis || The [[testes]] produce AMH and as a result the development of the Müllerian ducts is inhibited. || Disturbances can lead to [[persistent müllerian duct syndrome]]. || The ducts disappear except for the vestigial [[vagina masculina]] and the [[appendix testis]]. |
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| − | |- |
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| − | | female embryogenesis || The absence of AMH results in the development of female reproductive organs, as noted above. || Disturbance in the development may result in uterine absence ([[Mullerian agenesis]]) or [[uterine malformation]]s. || The ducts develop into the upper [[vagina]], [[cervix]], [[uterus]] and [[oviducts]]. |
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| − | |} |
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| − | ==Eponym== |
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| − | They are named after [[Johannes Peter Müller]], a [[physiologist]] who described these ducts in his text "Bildungsgeschichte der Genitalien" in [[1830]]. |
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| − | ==Additional images== |
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| − | <gallery> |
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| − | Image:Gray1107.png|Enlarged view from the front of the left Wolffian body before the establishment of the distinction of sex. |
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| − | Image:Gray1111.png|Transverse section of human embryo eight and a half to nine weeks old. |
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| − | </gallery> |
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| − | == See also == |
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| − | * [[Defeminization]] |
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| − | * [[prostatic utricle]] |
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| − | * [[List of homologues of the human reproductive system]] |
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| − | * [[Sexual differentiation]] |
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| − | * [[Wolffian duct]] |
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| − | ==External links== |
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| − | * {{EmbryologyUNC|genital|010}} |
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| − | {{Development of urinary and reproductive systems}} |
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| − | [[Category:Embryology|Muellerian duct]] |
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| − | [[Category:Developmental biology|Muellerian duct]] |
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| − | <!-- |
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| − | [[ru:Мюллеров проток]] |
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| − | {{enWP|Müllerian duct}} |
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Latest revision as of 15:41, 13 October 2013
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