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(New page: {{Biopsy}} {{Infobox Embryology | Name = {{PAGENAME}} | Latin = d. paramesonephricus | GraySubject = 252 | GrayPage = 1206 | Image = Gray1109.png ...)
 
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{{Infobox Embryology |
 
Name = {{PAGENAME}} |
 
Latin = d. paramesonephricus |
 
GraySubject = 252 |
 
GrayPage = 1206 |
 
Image = Gray1109.png |
 
Caption = [[Urogenital sinus]] of female human [[embryo]] of eight and a half to nine weeks old. |
 
Image2 = Gray993.png |
 
Caption2 = Tail end of human embryo, from eight and a half to nine weeks old. |
 
System = |
 
CarnegieStage = 17 |
 
Precursor = [[Intermediate mesoderm]] |
 
GivesRiseTo = |
 
MeshName = Mullerian+Ducts |
 
MeshNumber = A16.254.570 |
 
DorlandsPre = d_29 |
 
DorlandsSuf = 12315002 |
 
}}
 
The '''Müllerian ducts''' (or '''paramesonephric ducts''') are paired ducts of the [[embryo]] which run down the lateral sides of the [[urogenital ridge]] and terminate at the [[mullerian tubercle| mullerian eminence]] in the primitive urogenital sinus. In the female, it will develop to form the fallopian tubes, uterus, and the upper portion of the vagina. It is tissue of [[mesoderm|mesodermal ]] origin.
 
 
==Development==
 
[[Image:Gray1110.png|thumb|left|200px|Müllerian duct (blue) develops in females (middle image) and degenerates in males (bottom).]]
 
 
Müllerian duct develops in females and degenerates in males.
 
 
==Regulation of development==
 
The development of the Müllerian ducts is controlled by the presence or absence of "AMH", or [[Anti-müllerian hormone]] (also known as "MIF" for "Müllerian inhibiting factor", or "MIH" for "Müllerian inhibiting hormone").
 
 
{| class="wikitable"
 
| male embryogenesis || The [[testes]] produce AMH and as a result the development of the Müllerian ducts is inhibited. || Disturbances can lead to [[persistent müllerian duct syndrome]]. || The ducts disappear except for the vestigial [[vagina masculina]] and the [[appendix testis]].
 
|-
 
| female embryogenesis || The absence of AMH results in the development of female reproductive organs, as noted above. || Disturbance in the development may result in uterine absence ([[Mullerian agenesis]]) or [[uterine malformation]]s. || The ducts develop into the upper [[vagina]], [[cervix]], [[uterus]] and [[oviducts]].
 
|}
 
 
==Eponym==
 
They are named after [[Johannes Peter Müller]], a [[physiologist]] who described these ducts in his text "Bildungsgeschichte der Genitalien" in [[1830]].
 
 
==Additional images==
 
<gallery>
 
Image:Gray1107.png|Enlarged view from the front of the left Wolffian body before the establishment of the distinction of sex.
 
Image:Gray1111.png|Transverse section of human embryo eight and a half to nine weeks old.
 
</gallery>
 
 
== See also ==
 
* [[Defeminization]]
 
* [[prostatic utricle]]
 
* [[List of homologues of the human reproductive system]]
 
* [[Sexual differentiation]]
 
* [[Wolffian duct]]
 
 
==External links==
 
* {{EmbryologyUNC|genital|010}}
 
 
{{Development of urinary and reproductive systems}}
 
 
[[Category:Embryology|Muellerian duct]]
 
[[Category:Developmental biology|Muellerian duct]]
 
 
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[[ru:Мюллеров проток]]
 
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{{enWP|Müllerian duct}}
 

Latest revision as of 15:41, October 13, 2013

  1. redirectParamesonephric duct

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