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[[Image:|150px|Loxapine chemical structure]] Loxapine
IUPAC name
CAS number 1977-10-2	ATC code N05AH01
PubChem 3964	DrugBank APRD00574
Chemical formula	{{{chemical_formula}}}
Molecular weight	327.808 g/mol
Bioavailability
Metabolism
Elimination half-life	Oral-4 hours
Excretion	{{{excretion}}}
Pregnancy category
Legal status
Routes of administration

Loxapine (sold as Loxapac®, Loxitane®) is a typical antipsychotic medication, used primarily in the treatment of schizophrenia. It is a member of the dibenzodiazepine family and structurally related to clozapine. Several researchers have argued that Loxapine may behave as an atypical antipsychotic (PMID 10340686).

Loxapine may be metabolized by N-demethylation to amoxapine, a tetracyclic antidepressant (PMID 1860915).

[edit] Side effects

Side effects include tardive dyskinesia, neuroleptic malignant syndrome, extrapyramidal side effects, tremor and sedation.

This box: view • talk • edit Psycholeptics: antipsychotics (N05A)
Phenothiazine typical antipsychotics	Chlorpromazine • Fluphenazine • Mesoridazine • Perphenazine • Prochlorperazine • Promazine • Thioridazine/Sulforidazine • Trifluoperazine
Other typical antipsychotics	Indoles (Molindone) • Butyrophenones (Azaperone, Benperidol, Droperidol, Haloperidol) • Thioxanthenes (Flupentixol, Chlorprothixene, Thiothixene, Zuclopenthixol) • diphenylbutylpiperidines (Fluspirilene, Penfluridol, Pimozide) • other (Loxapine)
Atypical antipsychotics	Butyrophenones (Melperone) • Indoles (Sertindole, Ziprasidone) • Benzamides (Sulpiride, Remoxipride, Amisulpride) • diazepines/oxazepines/thiazepines (Clozapine, Olanzapine, Quetiapine) • other (Aripiprazole, Risperidone, Paliperidone, Zotepine)

This page uses content from the English-language version of Wikipedia. The original article was at Loxapine. The list of authors can be seen in the page history. As with Psychology Wiki, the text of Wikipedia is available under the GNU Free Documentation License.