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Longevity genes

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Confirmed Longevity Genes From Model AnimalsEdit

PodosporaSaccharomycesCaenorhabditisDrosophilaMouse
griseaLAG1daf-2sod1Prop-1
LAC1age-1/daf-23cat1p66shc
RAS1daf-18mth
RAS2akt-1/akt-2
PHB1daf-16
PHB2daf-12
CDC7ctl-1
BUD1old-1
RTG2spe-26
RPD3clk-1
HDA1mev-1
SIR2
SIR4-42
UTH4
YGL023
SGS1
RAD52
FOB1

The major genetic model organisms used in aging research are the filamentous fungus ('Podospora anserina'), bakers' yeast ('Saccharomyces cerevisiae'), the soil roundworm ('Caenorhabditis elegans'), the fruit fly ('Drosophila melanogaster'), and the mouse ('Mus musculus').

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