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Levomethamphetamine

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Levomethamphetamine chemical structure
Levomethamphetamine

(R)-N-methyl-1-phenyl-propan-2-amine
IUPAC name
CAS number
537-46-2
ATC code

[[ATC_code_|]][1]

PubChem
1206
DrugBank
[2]
Chemical formula {{{chemical_formula}}}
Molecular weight 149.2
Bioavailability
Metabolism Hepatic
Elimination half-life
Excretion Renal
Pregnancy category
Legal status OTC
Routes of administration Nasal Inhalation

Levomethamphetamine (other names: l-desoxyephedrine, l-methamphetamine, levmetamfetamine ) is the l- stereoisomer of methamphetamine, a sympathomimetic vasoconstrictor which is the active ingredient used in some over-the-counter nasal decongestants. The common brand-name for levmetamfetamine in the U.S. is the Vicks Inhaler. In the U.S., the name was converted to levmetamfetamine from levo-methamphetamine to lower the risk of abuse of the decongestant preparation.

ChemistryEdit

Levomethamphetamine mimicks the sympathetic nervous system but is not thought to be nearly as addictive or centrally active as the d- isomer of methamphetamine (dextro-methamphetamine, d-methamphetamine, d-desoxyephedrine, etc.) and only exerts vasoconstricting effects used for decongestion.

Side EffectsEdit

Common side effects include muscle tremor and stomach cramps. Other side effects include hypertension and tachycardia.

Recreational UseEdit

Although levo-methamphetamine is only very mildly centrally active (unlike dextro-methamphetamine, which acts mainly on the central nervous system), many recreational drug users abuse the inhaler preparation by cracking open the inhaler and then swallowing the cotton inside (as the cotton is soaked in levo-methamphetamine.) This gives the user a very mild "speedy" effect with a mild energy boost, similar to that of ephedrine or pseudoephedrine. Sometimes uncomfortable and displeasant feelings can arise by ingesting the cotton, since the cotton is also soaked in menthol and camphor. Both menthol and camphor are analgesics and can be possibly lethal at high doses.

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