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L-type calcium channel

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The L-type calcium channel is a type of voltage-dependent calcium channel. Like the others of this class, the α1 subunit is the one that determines most of the channel's properties.

L-type calcium channel blockers are used as antiarrhythmics or antihypertensives, depending on whether the drugs has higher affinity to the heart (like verapamil) or to the vessels (nifedipine).

L-type channels are selectively blocked by dihydropyridines.

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