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'''Iproniazid''' (''iproniazid phosphate'', marketed under the names '''Marsilid®''', '''Iprozid®''', '''Ipronid®''', '''Rivivol®''', '''Propilniazida®''') is a monamine oxidase inhibitor ([[MAOI]]) that was developed as the first anti-depressant. It was originally intended to treat tuberculosis when it was discovered that patients given iproniazid became "inappropriately happy," subsequently with further research iproniazid was marketed specifically for depression in 1958. It was later replaced by less hepatotoxic drugs. |
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'''Iproniazid''' (''iproniazid phosphate'', marketed under the names '''Marsilid®''', '''Iprozid®''', '''Ipronid®''', '''Rivivol®''', '''Propilniazida®''') is a monamine oxidase inhibitor ([[MAOI]]) that was developed as the first anti-depressant. It was originally intended to treat tuberculosis when it was discovered that patients given iproniazid became "inappropriately happy," subsequently with further research iproniazid was marketed specifically for depression in 1958. It was later replaced by less hepatotoxic drugs. |
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==See also== |
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*[[Amine oxidase inhibitors]] |
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*[[Antidepressant drugs]] |
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*[[Antihypertensicve drugs]] |
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*[[Antitubercular drugs]] |
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*[[Monoamine oxidase inhibitors]] |
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{{Antidepressants}} |
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{{Antidepressants}} |
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[[Category:Amine oxidase inhibitors]] |
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[[Category:Antidepressant drugs]] |
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[[Category:Antihypertensicve drugs]] |
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[[Category:Antitubercular drugs]] |
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[[Category:Monoamine oxidase inhibitors]] |
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[[Category:Monoamine oxidase inhibitors]] |
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[[Category:Hydrazines]] |
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[[Category:Hydrazines]] |
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Iproniazid (iproniazid phosphate, marketed under the names Marsilid®, Iprozid®, Ipronid®, Rivivol®, Propilniazida®) is a monamine oxidase inhibitor (MAOI) that was developed as the first anti-depressant. It was originally intended to treat tuberculosis when it was discovered that patients given iproniazid became "inappropriately happy," subsequently with further research iproniazid was marketed specifically for depression in 1958. It was later replaced by less hepatotoxic drugs.
| Antidepressants (ATC N06A) edit
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| Monoamine oxidase inhibitors (MAOI) | Harmaline, Iproclozide, Iproniazid, Isocarboxazid, Nialamide, Phenelzine, Selegiline, Toloxatone, Tranylcypromine
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| Reversible inhibitor of monoamine oxidase A (RIMA) | Brofaromine, Moclobemide
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| Dopamine reuptake inhibitor (DARI) | Amineptine, Phenmetrazine, Vanoxerine, Modafinil
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| Norepinephrine-dopamine reuptake inhibitors | Bupropion
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| Norepinephrine reuptake inhibitor (NRI) or (NARI) | Atomoxetine, Maprotiline, Reboxetine, Viloxazine
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| Serotonin-norepinephrine reuptake inhibitor (SNRI) | Duloxetine, Milnacipran, Venlafaxine
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| Selective serotonin reuptake inhibitor (SSRI) | Alaproclate, Etoperidone, Citalopram, Escitalopram, Fluoxetine, Fluvoxamine, Paroxetine, Sertraline, Zimelidine
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| Selective serotonin reuptake enhancer (SSRE) | Tianeptine
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| Tricyclic antidepressants (TCA) | Amitriptyline, Amoxapine, Butriptyline, Clomipramine, Desipramine, Dibenzepin, Dothiepin, Doxepin, Imipramine, Iprindole, Lofepramine, Melitracen, Nortriptyline, Opipramol, Protriptyline, Trimipramine
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| Tetracyclic antidepressants | Maprotiline, Mianserin, Nefazodone, Trazodone
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| Noradrenergic and specific serotonergic antidepressant (NaSSA) Mirtazapine
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Edit